SIRPG Antibody

• Background:

  The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described.

• NCBI Gene ID:

  55423

• Swiss Prot:

  Q9P1W8

• Accession Number:

  Q9P1W8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SIRPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-221 amino acids from the Central region of human SIRPG.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  42 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SIRPG

• NCBI Official Name:

  Signal-regulatory protein gamma

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Barrett, J.C., et al. Nat. Genet. 41 (6) :703-707 (2009)

• Background Reference 02:

  Kawasaki, M., et al. Clin. Exp. Rheumatol. 27 (2) :260-266 (2009)

• Background Reference 03:

  Stefanidakis, M., et al. Blood 112 (4) :1280-1289 (2008)

• Background Reference 04:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Other Product Names:

  Signal-regulatory protein gamma, SIRP-gamma, CD172 antigen-like family member B, Signal-regulatory protein beta-2, SIRP-b2, SIRP-beta-2, CD172g, SIRPG, SIRPB2

• Tested Applications:

  WB

• Protein ID:

  124053651

• Physical Properties:

  Liquid