NEU-1 Recombinant Protein

• Background:

  Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues; it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), beta -galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex.

• NCBI Gene ID:

  4758

• Swiss Prot:

  Q99519

• Accession Number:

  Q99519

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Obesity, Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  41.27 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Neuraminidase 1 (lysosomal sialidase)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Sialidase-1, Acetylneuraminyl Hydrolase, G9 Sialidase, Lysosomal Sialidase, N-Acetyl-Alpha-Neuraminidase 1, NEU1, NANH

• Species:

  Human

• Protein ID:

  530363504

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3