S100P Recombinant Protein

• Background:

  S100 calcium-binding protein P (S100P), a member of the S-100 family, is also known as protein S100-P, migration-inducing gene 9 protein (MIG9) and protein S100-E, which contains two EF-hand domains. As for subunit structure, S100P is homodimer and heterodimer with S100A1. S100P may function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, S100P functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. Furthermore, S100P may stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE) .

• NCBI Gene ID:

  6286

• Swiss Prot:

  P25815

• Accession Number:

  AAH06819

• Tag:

  Tag free

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Purity:

  >95% as determined by SDS-PAGE.

• Buffer:

  50 mM Tris,150 mM Nacl, pH8.0

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  10.4 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  S100 calcium binding protein P

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Becker T., et al., 1992, Eur. J. Biochem. 207:541-547.

• Background Reference 02:

  Koltzscher M., et al., 2003, Mol. Biol. Cell 14:2372-2384.

• Background Reference 03:

  Arumugam T., et al., 2004, J. Biol. Chem. 279:5059-5065.

• Other Product Names:

  S100P, S100E, MIG9

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3