RANTES Recombinant Protein

• Background:

  RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV) . Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

• NCBI Gene ID:

  6352

• Swiss Prot:

  P13501

• Accession Number:

  NP_002976.2

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Chemokines & Cytokines, Immunology, Innate Immunity

• Purity:

  Greater than 98% by SDS-PAGE gel and HPLC analyses.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized RANTES recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted RANTES stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing RANTES recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Chemokine (C-C motif) ligand 5

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  SISd, eoCP, SCYA5, RANTES, TCP228, D17S136E, SIS-delta, C-C motif chemokine 5, EoCP

• Species:

  Human

• Protein ID:

  22538814

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3