RANTES Antibody [5B3-D5]

• Background:

  RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV) . It is T cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.

• NCBI Gene ID:

  6352

• Swiss Prot:

  P13501

• Accession Number:

  P13501

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Monoclonal antibody against human RANTES designated as VL-1 was purified from ascites fluid on a Protein A affinity column.

• Clonality:

  Monoclonal

• Clone:

  5B3-D5

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies, Functional Antibodies

• Field of Research:

  Chemokines & Cytokines

• Concentration:

  Batch dependent

• Modification:

  None

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  RANTES lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20˚ C. Reconstitute in sterile water to a concentration of 0.1 - 1.0 mg/mL. The antibody is stable for at least six weeks at 2-4˚ C when reconstituted.

• Fragment:

  RANTES antibody was derived form BALB/c mice and belongs to the IgG2b isotype.

• Symbol:

  CCL5

• NCBI Official Name:

  Chemokine (C-C motif) ligand 5

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Regulated upon activation normally T expressed and presumably secreted, CCL5, TCP228, SISd, D17S136E, SCYA5, C-C motif chemokine 5, EoCP, eoCP, RANTES, SIS-delta

• Tested Applications:

  ELISA, WB, Neutralization Assay

• Protein ID:

  6175077

• Physical Properties:

  Lyophilized