RANTES Antibody

• Background:

  RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV) . It is T cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.

• NCBI Gene ID:

  20304

• Swiss Prot:

  P30882

• Accession Number:

  P30882

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mRANTES (murine RANTES) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies, Functional Antibodies, Antibody Pairs

• Field of Research:

  Chemokines & Cytokines

• Purification:

  Anti-mRANTES specific antibody was purified by affinity chromatography employing immobilized mRANTES matrix.

• Concentration:

  Batch dependent

• Modification:

  None

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  RANTES antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

• Symbol:

  Ccl5

• NCBI Official Name:

  Chemokine (C-C motif) ligand 5

• NCBI Organism:

  Mus musculus

• Other Product Names:

  SISd, Scya5, RANTES, TCP228, MuRantes, C-C motif chemokine 5

• Tested Applications:

  ELISA, WB, Neutralization Assay

• Protein ID:

  548926

• Physical Properties:

  Lyophilized