Ro 23-9424

• Description:

  Ro 23-9424 is a broad-spectrum cephalosporin composed of a cephalosporin and a quinolone moiety. Ro 23-9424 shows antimicrobial activity in vivo and in vitro[1][2][3].

• UNSPSC:

  12352005

• Target:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/ro-23-9424.html

• Smiles:

  O=C(C(N12)=C(COC(C3=CN(CCF)C4=C(C=C(F)C(N5CCN(C)CC5)=C4F)C3=O)=O)CS[C@]2([H])[C@H](NC(/C(C6=CSC(N)=N6)=N\OC)=O)C1=O)O

• Molecular Formula:

  C31H31F3N8O8S2

• Molecular Weight:

  764.75

• References & Citations:

  [1]Pfaller MA, et al. RO 23-9424, a new cephalosporin 3'-quinolone: in-vitro antimicrobial activity and tentative disc diffusion interpretive criteria. J Antimicrob Chemother. 1993;31 (1) :81-88. |[2]Christenson JG, et al. Pharmacokinetics of Ro 23-9424, a dual-action cephalosporin, in animals. Antimicrob Agents Chemother. 1990;34 (10) :1895-1900.|[3]Matera G, et al. Effect of RO 23-9424, cefotaxime and fleroxacin on functions of human polymorphonuclear cells and cytokine production by human monocytes. J Antimicrob Chemother. 1996;38 (5) :799-807.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• Isoform:

  Quinolone

• CAS Number:

  [115622-58-7]