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Ro 23-9424

CAT: 0804-HY-123271Size: 1 EachDry Ice: NoHazardous: No
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Description
Ro 23-9424 is a broad-spectrum cephalosporin composed of a cephalosporin and a quinolone moiety. Ro 23-9424 shows antimicrobial activity in vivo and in vitro[1][2][3].
CAS Number
115622-58-7
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ro-23-9424.html
Smiles
O=C(C(N12)=C(COC(C3=CN(CCF)C4=C(C=C(F)C(N5CCN(C)CC5)=C4F)C3=O)=O)CS[C@]2([H])[C@H](NC(/C(C6=CSC(N)=N6)=N\OC)=O)C1=O)O
Molecular Formula
C31H31F3N8O8S2
Molecular Weight
764.75
References & Citations
[1]Pfaller MA, et al. RO 23-9424, a new cephalosporin 3'-quinolone: in-vitro antimicrobial activity and tentative disc diffusion interpretive criteria. J Antimicrob Chemother. 1993;31 (1) :81-88. |[2]Christenson JG, et al. Pharmacokinetics of Ro 23-9424, a dual-action cephalosporin, in animals. Antimicrob Agents Chemother. 1990;34 (10) :1895-1900.|[3]Matera G, et al. Effect of RO 23-9424, cefotaxime and fleroxacin on functions of human polymorphonuclear cells and cytokine production by human monocytes. J Antimicrob Chemother. 1996;38 (5) :799-807.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
Quinolone

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