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NME1 Recombinant Protein

CAT: 0223-96-932Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-96-932Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Nucleoside diphosphate kinase A, a member of the NDK family, is also known as NME1, NDP kinase A (NDPA), granzyme A-activated DNase (GAAD), metastasis inhibition factor nm23 (NM23-H1) and tumor metastatic process-associated protein. NME1 plays a major role in the synthesis of nucleoside triphosphates other than ATP. NME1 is also involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Furthermore, NME1 is required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, NME1 works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair.
CAS Number
9000-83-3
NCBI Gene ID
4830
Swiss Prot
P15531-1
Accession Number
AAH00293
Tag
His Tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Other
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
18 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Non-metastatic cells 1, protein (NM23A)
NCBI Organism
Homo sapiens
Background Reference 01
Rosengard A.M., et al., 1989, Nature 342:177-180.
Background Reference 02
Fan Z., et al., 2003, Cell 112:659-672.
Background Reference 03
Min K., et al., 2002, Proteins 46:340-342.
Other Product Names
NME1, NDP kinase A, NDPA, GAAD, NM23-H1
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized

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