NRG1‑beta 1 Recombinant Protein

• Background:

  Neuregulin-1 (heregulin-1, NRG1) is a member of neuregulin family, which is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. NRG1 isoforms can be classified into type I, type II and type III isoforms. NRG1 directs ligand for ERBB3 and ERBB4 tyrosine kinase receptors, concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart.

• NCBI Gene ID:

  3084

• Swiss Prot:

  Q02297-6

• Accession Number:

  Q02297-6

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer, Cell Cycle, Neuroscience, Signal Transduction, Other

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 4mM HCl. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  29 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Neuregulin 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Pro-neuregulin-1, Neuregulin-1 beta 1, NRG1-beta 1, HRG1-beta 1 ECD, EGF, NRG1, GGF, HGL, HRGA, NDF, SMDF, HRG1‑beta 1

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3