Nectin-2 Recombinant Protein

• Background:

  Nectin-2 (CD112) is a member of the nectin family, which contains two Ig-like C2-type domains and one Ig-like V-type domain in the extracellular region. Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig) -like cell adhesion molecules (CAMs) . Nectin2 is widely expressed in human tissues including brain, spinal cord, spleen, kidney, heart and liver. It can form trans-heterodimers with PVRL3/nectin-3 and interacts with CD226. Mutations of alleles of the murine CD112 gene can result in conditions such as morphologically aberrant spermatozoa. It may function in allergic reactions, and accordingly may used as a novel target for anti-allergic therapy.

• NCBI Gene ID:

  19294

• Swiss Prot:

  P32507

• Accession Number:

  P32507

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  35.6 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Poliovirus receptor-related 2

• NCBI Organism:

  Mus musculus

• Other Product Names:

  CD112/nectin2 /Herpes virus entry mediator B/Herpesvirus entry mediator B/HveB/Murine herpes virus entry protein B/mHveB/Poliovirus receptor homolog/Poliovirus receptor-related protein 2/Pvrl2/Pvr/Mph/Pvs, CD112, PVRL2

• Species:

  Mouse

• Protein ID:

  618854972

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3