ACE-2 Recombinant Protein

• Background:

  Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.

• NCBI Gene ID:

  59272

• Swiss Prot:

  Q9BYF1

• Accession Number:

  Q9BYF1

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Infectious Disease, Innate Immunity, Obesity, Other

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mMTris,300mMNacl,1mMZncl2,10%Glycerol, PH7.4 .

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  84.63 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Angiotensin I converting enzyme 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3