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Nectin-4 Recombinant Protein

CAT: 0223-92-421Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-421Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.
CAS Number
9000-83-3
NCBI Gene ID
81607
Swiss Prot
Q96NY8
Accession Number
Q96NY8
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cell Cycle
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
35.3 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Nectin cell adhesion molecule 4
NCBI Organism
Homo sapiens
Other Product Names
PVRL4/Nectin-4/Ig superfamily receptor LNIR/Poliovirus receptor-related protein 4/PRR4/LNIR, PVRL4
Species
Human
Protein ID
530363504
Physical Properties
Lyophilized

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