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MGMT Recombinant Protein

CAT: 0223-92-212Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-92-212Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. MGMT catalyzes the chemical reaction: DNA (containing 6-O-methylguanine) and proteinL-cysteine into DNA (without 6-O-methylguanine) and protein S-methyl-L-cysteine.
CAS Number
9000-83-3
NCBI Gene ID
4255
Swiss Prot
P16455
Accession Number
P16455
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Other
Buffer
Supplied as a 0.2 um filtered solution of 20mMTrisHCl,1mM EDTA, pH 8.0 . It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
23.8 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
O-6-methylguanine-DNA methyltransferase
NCBI Organism
Homo sapiens
Other Product Names
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNAmethyltransferase, O-6-methylguanine-DNA-alkyltransferase, MGMT
Species
Human
Protein ID
530394832
Physical Properties
Liquid

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