LYPD3 Recombinant Protein

• Background:

  Ly6/PLAUR domain-containing protein 3 (LYPD3) is also known as MIG-C4 , C4.4A, GPI-anchored metastasis-associated protein C4.4A homolog and Matrigel-induced gene C4 protein, which is a cell membrane protein containing two UPAR/Ly6 domains. LYPD3 is expressed in placenta, skin and urothelium. LYPD3 is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. LYPD3 play a role in supporting cell migration and it is not only probably involved in urothelial cell-matrix interactions, but also in tumor progression.

• NCBI Gene ID:

  27076

• Swiss Prot:

  O95274

• Accession Number:

  AAH39167

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Cancer, Other

• Purity:

  >95% as determined by SDS-PAGE.

• Buffer:

  PBS, pH7.4

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  28.7 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  LY6/PLAUR domain containing 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hansen L.V., et al., 2004, Biochem. Eng. J. 380:845-857.

• Background Reference 02:

  Fletcher G.C., et al., 2003, Br. J. Cancer 88:579-585.

• Background Reference 03:

  Oshiro R., et al., 2012, Cancer Sci. 103:1155-1164.

• Other Product Names:

  LYPD3, MIG-C4, C4.4A

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3