Jagged-2 Recombinant Protein

• Background:

  Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.

• NCBI Gene ID:

  3714

• Swiss Prot:

  Q61483

• Accession Number:

  Q9Y219

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Cancer, Neuroscience, Obesity, Signal Transduction

• Concentration:

  0.1mg/ml after reconstitution.

• Buffer:

  Contains PBS + 0.02 % CHAPS. Reconstitute with 100 μ l sterile water.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Stable for at least 6 months after receipt when stored at -20˚ C.

• Applications Notes:

  This recombinant proteins is for research use only.

• NCBI Official Name:

  Jagged 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Protein Jagged-2, hJ2, JAG2

• Species:

  Human

• Protein ID:

  21704277

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3