Products for Research Use Only

Jagged-1 Recombinant Protein

CAT: 0223-91-812Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-812Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Protein jagged-1 I, also known as Jagged-1, JAGL1, HJ1, JAG1 and CD339, is a single-pass type I membrane protein. JAG1 contains one DSL domain and sixteen EGF-like domain. JAG1 acts as a ligand for multiple Notch receptors and is involved in the mediation of Notch signaling. JAG1 may participate in early and late stages of mammalian cardiovascular development, JAG1 inhibits myoblast differentiation and enhances fibroblast growth factor-induced angiogenesis. Defects in JAG1 are the cause of Alagille syndrome type 1, which is autosomal dominant multisystem disorder defined clinically by hepatic bile duct paucity and cholestasis in association with cardiac, skeletal, and ophthalmologic manifestations.
CAS Number
9000-83-3
NCBI Gene ID
182
Swiss Prot
P78504
Accession Number
P78504
Tag
C-Fc tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Cell Cycle, Neuroscience, Stem Cell
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
138.5 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Jagged 1
NCBI Organism
Homo sapiens
Other Product Names
Protein jagged-1 I, Jagged-1, JAGL1, HJ1, JAG1 and CD339, JAG1, CD339
Species
Human
Physical Properties
Lyophilized