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Jagged 1 Recombinant Protein

CAT: 0223-96-482Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-96-482Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Protein jagged-1 (JAG1) is also known as Jagged1, hJ1, JAGL1 and CD339, which is a single-pass type I membrane protein containing one DSL domain and 15 EGF-like domains. JAG1 is widely expressed in adult and fetal tissues, the expression of JAG1 is up-regulated in cervical squamous cell carcinoma and also expressed in bone marrow cell line HS-27a.JAG1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. JAG1 is involved in early and late stages of mammalian cardiovascular development. JAG1 inhibits myoblast differentiation by similarity and enhances fibroblast growth factor-induced angiogenesis (in vitro) .
CAS Number
9000-83-3
NCBI Gene ID
182
Swiss Prot
P78504
Accession Number
NP_000205
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cancer, Cell Cycle, Neuroscience, Stem Cell
Purity
>92% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
112.3 kDa
NCBI Official Name
Jagged 1
NCBI Organism
Homo sapiens
Background Reference 01
Li L., et al., 1998, Immunity 8:43-55.
Background Reference 02
Bash J., et al., 1999, EMBO J. 18:2803-2811.
Background Reference 03
Zimrin A.B., et al., 1996, J. Biol. Chem. 271:32499-32502.
Other Product Names
CD339, JAG1, Jagged1, hJ1, JAGL1
Species
Human
Physical Properties
Lyophilized

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