IL-4 Recombinant Protein

• Background:

  Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.

• NCBI Gene ID:

  3565

• Swiss Prot:

  P05112

• Accession Number:

  P05112

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Cancer, Chemokines & Cytokines, Growth Factors, Immunology, Innate Immunity, Signal Transduction

• Buffer:

  Lyophilized from a 0.2 um filtered solution of PBS, PH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  16 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Interleukin 4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Interleukin-4, IL-4, B-Cell Stimulatory Factor 1, BSF-1, Binetrakin, Lymphocyte Stimulatory Factor 1, Pitrakinra, IL4

• Species:

  Human

• Protein ID:

  189065303

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3