Equine IL-4 Recombinant Protein

• Background:

  IL-4 induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4. IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. IL-4 induces B-cell class switching to IgE, and up-regulates MHC class II production. Overproduction of IL-4 is associated with allergies.

• Description:

  The Equine IL-4 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Equine IL-4 applications are for cell culture, ELISA standard, and Western Blot Control. The Equine IL-4 yeast-derived recombinant protein can be purchased in multiple sizes. Equine IL-4 Specifications: (Molecular Weight: 12.8 kda) (Amino Acid Sequence: GCKYDITLQE IIKTLNNLTD GKGKNSCMEL TVADAFAGPK NTDGKEICRA AKVLQQLYKR HDRSLIKECL SGLDRNLKGM ANGTCCTVNE AKKSTLKDFL ERLKTIMKEK YSKC) . For research use only.

• Applications:

  Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control

• Homology:

  Equus asinus (ass), Equus caballus (horse), Equus przewalskii (Przewalski's horse), Equus zebra hartmannae (Hartmann's mountain zebra)

• Storage Temperature:

  -20°C