CD54 [ICAM-1] non-lytic Recombinant Protein

• Background:

  Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac1. CD54 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1beta and LPS. Soluble CD54 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, LAD, cancer and transplantation.

• NCBI Gene ID:

  3383

• Swiss Prot:

  Q9Y6W8

• Accession Number:

  NP_000192

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  CHO cells

• Field of Research:

  Immunology, Signal Transduction

• Buffer:

  Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μ g/ml in sterile PBS.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.

• Applications Notes:

  This recombinant proteins is for research use only.

• NCBI Official Name:

  Intercellular adhesion molecule 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ICAM1, Intercellular Adhesion Molecule 1

• Species:

  Human

• Protein ID:

  167466198

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3