Intelectin-1 Recombinant Protein

• Background:

  Intelectin-1 (ITLN1) is a secreted protein and contains 1 fibrinogen C-terminal domain. Intelectin-1 is a 40 kDa Ca-dependent galactofuranose-binding lectin that is not a C-type lectin. It is expressed on multiple cell types and appears to participate in insulin signaling and microbe recognition. The protein has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin and it may play a role in the defense systemagainst microorganisms. It also may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosy l residues, in a calcium-dependent manner.

• NCBI Gene ID:

  55600

• Swiss Prot:

  Q8WWA0

• Accession Number:

  Q8WWA0

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Innate Immunity, Obesity

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 50mM Tris,100mMNaCl, 5mM GSH, 0.5mM GSSG, pH8.0 . It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  32.7 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Intelectin 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Intelectin-1, ITLN-1, Endothelial lectin HL-1, Galactofuranose-binding lectin, Intestinal lactoferrin receptor, Omentin, INTL, ITLN, LFR

• Species:

  Human

• Protein ID:

  530384505

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3