Dectin-1 Recombinant Protein

• Background:

  Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM) -like motif in the cytoplasmic domain, whereas dectin-2 recognizes alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.

• NCBI Gene ID:

  56644

• Swiss Prot:

  P19838

• Accession Number:

  Q6QLQ4

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Concentration:

  1mg/ml after reconstitution.

• Buffer:

  Contains PBS. Reconstitute with 50 μ l sterile water.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Stable for at least 6 months after receipt when stored at -20˚ C.

• Applications Notes:

  This recombinant proteins is for research use only.

• NCBI Official Name:

  C-type lectin domain family 7, member a

• NCBI Organism:

  Mus musculus

• Other Product Names:

  C-type Lectin Domain Family 7 Member A, Beta-Glucan Receptor, Dendritic Cell-associated C-type Lectin 1, C-type Lectin Superfamily Member 12, DC-associated C-type Lectin 1

• Species:

  Mouse

• Protein ID:

  408360305

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3