Inositol Monophosphatase 2 Recombinant Protein

• Background:

  Inositol monophosphatase 2, also known as Inositol-1 (or 4) -monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA2 is a pharmacological target for lithium Li (+) action in brain, it is considered to have a role in schizophrenia and bipolar disorder.

• NCBI Gene ID:

  3613

• Swiss Prot:

  O14732

• Accession Number:

  O14732

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM Tris, 2mM DTT, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  33.5 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Inositol monophosphatase 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Inositol Monophosphatase 2, IMP 2, IMPase 2, Inositol-1 (or 4) -Monophosphatase 2, Myo-Inositol Monophosphatase A2, IMPA2, IMP.18P

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3