Inositol Monophosphatase 1 Recombinant Protein

• Background:

  Inositol Monophosphatase 1 (IMPA1) belongs to the inositol monophosphatase family. IMPA1 is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides, IMPA1 can use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2-AMP as substrates. IMPA1 has been implicated as the pharmacological target for lithium action in brain. IMPA1 shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. In addition, IMPA1 plays a improtant role in intracellular signal transduction.

• NCBI Gene ID:

  3612

• Swiss Prot:

  P29218

• Accession Number:

  P29218

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.25. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  32.3 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Inositol monophosphatase 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Inositol Monophosphatase 1, IMP 1, IMPase 1, Inositol-1 (or 4) -Monophosphatase 1, Lithium-Sensitive Myo-Inositol Monophosphatase A1, IMPA1, IMPA, IIMPase 2

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3