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ApoE3 Recombinant Protein

CAT: 0223-40-136-01Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-40-136-01Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ApoE3 belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. E3 is the most common isoform and is present in 40-90% of the population. Recombinant human ApoE3 is a 34.4 kDa protein containing 300 amino acid residues.
NCBI Gene ID
348
Swiss Prot
P02649
Accession Number
NP_000032.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Infectious Disease, Neuroscience
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized ApoE3 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted ApoE3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing ApoE3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Apolipoprotein E
NCBI Organism
Homo sapiens
Other Product Names
AD2, LPG, LDLCQ5, Apolipoprotein E, Apo-E
Species
Human
Protein ID
4557325
Physical Properties
Lyophilized

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