Granzyme B Recombinant Protein

• Background:

  Granzyme B (GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

• NCBI Gene ID:

  14939

• Swiss Prot:

  P04187

• Accession Number:

  P04187

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Buffer:

  Supplied as a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  26.5 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Granzyme B

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Granzyme B (G, H), CTLA-1, Cytotoxic cell protease 1, CCP1, Fragmentin-2, Gzmb, Ctla1

• Species:

  Mouse

• Protein ID:

  767957252

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3