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Granzyme B Recombinant Protein

CAT: 0013-GTR18911808-01Size: 0.002 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18911808-01Size:0.002 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Granzyme B Recombinant Protein
Product Name Alternative
GZB, CCP1, Ctla1, Ctla-1, AI553453, CCP-1/C11, CTLA-1
UniProt
P04187
Source
Baculovirus
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg) .
Bioactivity
Determined by its ability to cleave a synthetic chromogentic Granzyme B substrate. The expected specific activity, when using the Ac - IEPD - pNA substrate at 25 ̊C, is greater than 750 nM/min per μg of enzyme.
Form
Lyophilized
Storage Conditions
The lyophilized Granzyme B recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Granzyme B is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Granzyme B recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Notes
For research use only.
NCBI Accession Number
NP_038570.1
AA Sequence
IIGGHEVKPH SRPYMALLSI KDQQPEAICG GFLIREDFVL TAAHCEGSII NVTLGAHNIK EQEKTQQVIP MVKCIPHPDY NPKTFSNDIM LLKLKSKAKR TRAVRPLNLP RRNVNVKPGD VCYVAGWGRM APMGKYSNTL QEVELTVQKD RECESYFKNR YNKTNQICAG DPKTKRASFR GDSGGPLVCK KVAAGIVSYG YKDGSPPRAF TKVSSFLSWI KKTMKSS

UniProtKB · P04187

Granzyme B(G,H)

GRAB_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P04187
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Gzmb
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
3.4.21.79
Processing
Precursor
Secondary accessions
—
Protein keywords

Biological process

ApoptosisCytolysis

Technical term

Direct protein sequencingReference proteome

PTM

Disulfide bondGlycoproteinZymogen

Molecular function

HydrolaseProteaseSerine protease

Cellular component

LysosomeSecreted

Domain

Signal

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