Products for Research Use Only
RegisterLogin

EPCR Recombinant Protein

CAT: 0223-91-315Size: 0.05 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-91-315Size:0.05 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Endothelial Protein C Receptor (EPCR) is a Vitamin K-dependent Serine Protease that plays a major role in blood coagulation. Binding of Protein C to EPCR leads to the proteolytic activation of PAR1 (Protease-Activated Receptor 1) on endothelial cells and subsequent up-regulation of Protein C-induced genes. EPCR is a type I transmembrane glycoprotein in the CD1/MHC family. It is expressed most strongly in the endothelial cells of arteries and veins in heart and lung. Membrane bound EPCR is released by metalloproteolytic cleavage to generate the soluble receptor. The extracellular domain of human and mouse EPCR shares approximately 61% amino acid sequence homology. EPCR plays an important role in augmenting Protein C activation by the Thrombin-Thrombomodulin complex and in regulating blood coagulation and inflammation. EPCR is found primarily on endothelial cells. Deletion of EPCR function results in embryonic death, at least in part due to placental thrombosis.
CAS Number
9000-83-3
NCBI Gene ID
10544
Swiss Prot
Q9UNN8
Accession Number
Q9UNN8
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
23.06 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Protein C receptor
NCBI Organism
Homo sapiens
Other Product Names
Endothelial Protein C Receptor, Activated Protein C Receptor, APC Receptor, Endothelial Cell Protein C Receptor, CD201, PROCR, EPCR
Species
Human
Physical Properties
Lyophilized

Related Products

CatalogName
96-364Glyco Recombinant Protein A33 Recombinant Protein
96-361Glyco Recombinant Protein A33 Recombinant Protein
92-035Recombinant Humanp21 Recombinant Protein
91-235Protein CutA Recombinant Protein
91-317Protein FAM3C Recombinant Protein
91-318Protein FAM3D Recombinant Protein
96-655Protein G Recombinant Protein
96-656Protein L Recombinant Protein
40-581-01Midkine Recombinant Protein
40-571-01Osteonectin Recombinant Protein

Alternative Products

CatalogName
GTR18908780EPCR Recombinant Protein
PROTQ9UNN8-50ugHuman EPCR Recombinant Protein
NBP2-59896-250ugRecombinant Human EPCR Protein
NBP1-88168PEPEPCR Recombinant Protein Antigen
TMPY-03192-01EPCR Protein, Human, Recombinant (hFc)
TMPY-03594-01EPCR Protein, Cynomolgus, Recombinant (His)
TMPY-03347-01EPCR Protein, Rat, Recombinant (His)
TMPY-02489-01EPCR Protein, Mouse, Recombinant (hFc)
TMPY-02487-01EPCR Protein, Mouse, Recombinant (His)
TMPY-03832-01EPCR Protein, Cynomolgus, Recombinant (hFc)

Popular Products