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EPCR Recombinant Protein

CAT: 0223-96-636Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-96-636Size:0.1 mg
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Background
Endothelial protein C receptor (PROCR) is also known as Activated protein C receptor (APC receptor), Endothelial cell protein C receptor, CD antigen CD201. PROCR / EPCR / CD201 is a N-glycosylated protein, with a soluble form exists. PROCR is probably released by a metalloprotease. PROCR seems to have the same activity as the membrane-bound form. PROCR / EPCR / CD201 is expressed strongly in the endothelial cells of arteries and veins in heart and lung. PROCR binds activated protein C and enhances protein C activation by the thrombin - thrombomodulin complex. PROCR plays a role in the protein C pathway controlling blood coagulation.
CAS Number
9000-83-3
NCBI Gene ID
10544
Swiss Prot
Q9UNN8
Accession Number
AAH14451
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Signal Transduction
Purity
>95% as determined by SDS-PAGE.
Buffer
50 mM tris, 100 mM glycine, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
48.6 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Protein C receptor, endothelial
NCBI Organism
Homo sapiens
Background Reference 01
Fukudome K., et al., 1994, J. Biol. Chem. 269:26486-26491.
Background Reference 02
Oganesyan V., et al., 2002, J. Biol. Chem. 277:24851-24854.
Other Product Names
PROCR, EPCR, CD201, APC receptor, CCCA, CCD41
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized

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