EPCR Recombinant Protein

• Background:

  Endothelial protein C receptor (PROCR) is also known as Activated protein C receptor (APC receptor), Endothelial cell protein C receptor, CD antigen CD201. PROCR / EPCR / CD201 is a N-glycosylated protein, with a soluble form exists. PROCR is probably released by a metalloprotease. PROCR seems to have the same activity as the membrane-bound form. PROCR / EPCR / CD201 is expressed strongly in the endothelial cells of arteries and veins in heart and lung. PROCR binds activated protein C and enhances protein C activation by the thrombin - thrombomodulin complex. PROCR plays a role in the protein C pathway controlling blood coagulation.

• NCBI Gene ID:

  10544

• Swiss Prot:

  Q9UNN8

• Accession Number:

  AAH14451

• Tag:

  C-Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Signal Transduction

• Purity:

  >95% as determined by SDS-PAGE.

• Buffer:

  50 mM tris, 100 mM glycine, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  48.6 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Protein C receptor, endothelial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Fukudome K., et al., 1994, J. Biol. Chem. 269:26486-26491.

• Background Reference 02:

  Oganesyan V., et al., 2002, J. Biol. Chem. 277:24851-24854.

• Other Product Names:

  PROCR, EPCR, CD201, APC receptor, CCCA, CCD41

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3