EDIL3 Recombinant Protein

CAT: 0223-91-534Size: 0.05 mgDry Ice: NoHazardous: No
CAT#:0223-91-534Size:0.05 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
EGF-Like Repeat and Discoidin I-Like Domain-Containing Protein 3 (EDIL3) is a 52 kDa extracellular matrix protein that is expressed by endothelial tissues during embryonic vascular development. EDIL3 becomes quiescent at the time of birth, and is no longer expressed in normal adult tissues. EDIL3 has been found to be re-expressed in a number of human tumors as well as in ischemic muscles and ischemic brain tissue, which may play an important role in adult angiogenesis. EDIL3 promotes adherence and migration of endothelial cells, and acts as an endothelial cell survival agent through upregulation of Bcl-2 expression. EDIL3 has also been shown to be an endogenous inhibitor of inflammatory cell recruitment by interfering with the integrin LFA-1-dependent leukocyte-endothelial adhesion. Human EDIL3 is synthesized as a precursor with a 16 amino acid signal sequence and a 464 amino acid mature chain.
CAS Number
9000-83-3
NCBI Gene ID
10085
Swiss Prot
Q8N610
Accession Number
Q8N610
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
53.09 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
EGF like repeats and discoidin domains 3
NCBI Organism
Homo sapiens
Other Product Names
EGF-Like Repeats and Discoidin I-Like Domains 3, EDIL3, Del-1
Species
Human
Protein ID
929654682
Physical Properties
Lyophilized

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