Delta4 Recombinant Protein

• Background:

  Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4) . DLL4 contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 plays a role in the Notch signaling pathway. DLL4 activates Notch-1 and Notch-4.

• NCBI Gene ID:

  54567

• Swiss Prot:

  Q9NR61

• Accession Number:

  NP_061947.1

• Tag:

  C-Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Cancer, Chemokines & Cytokines, Immunology, Stem Cell

• Purity:

  >95% as determined by SDS-PAGE.

• Buffer:

  Tris with Glycine, Arginine and NaCl, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  81 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Delta-like 4 (Drosophila)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zhang Z., et al., 2004, Protein Sci. 13:2819-2824.

• Background Reference 02:

  Brutsch R., et al., 2010, Circ. Res. 107:592-601.

• Other Product Names:

  Delta 4, DLL4

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3