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DcR3 Recombinant Protein

CAT: 0223-90-454Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0223-90-454Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Decoy receptor 3 (DcR3; TNFRSF6B; M68) is a member of the TNF receptor superfamily. DcR3 shares sequence identity with OPG (31%), TNF-RII (29%) and Fas (17%) and is expressed in a variety of different tissues and at high levels in many malignant tumors. Ligands of DcR3 include Fas ligand, homologous to lymphotoxin showing inducible expression and competing with HSV glycoprotein D for herpes virus entry mediator (a receptor expressed by T lymphocytes), TNF-like molecule 1A and heparan sulfate proteoglycans. DcR3 modulates the function of T cells, dendritic cells and macrophages. DcR3/Fc fusion proteins can bind to human and mouse B cells and suppress the activation of B cells.
CAS Number
9000-83-3
NCBI Gene ID
8771
Swiss Prot
P29460
Accession Number
O95407
Tag
Fc Tag
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Apoptosis
Buffer
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute with 100 μ l sterile water. Add 1X PBS to the desired protein concentration.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Tumor necrosis factor receptor superfamily, member 6b, decoy
NCBI Organism
Homo sapiens
Other Product Names
Decoy Receptor 3, Tumor Necrosis Factor Receptor Superfamily Member 6B, TNFRSF6B, M68
Species
Human
Protein ID
4106877
Physical Properties
Lyophilized

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