CDCP1 Recombinant Protein

CAT: 0223-92-385Size: 0.05 mgDry Ice: NoHazardous: No
CAT#:0223-92-385Size:0.05 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CUB domain-containing protein 1 (CDCP1) is a transmembrane glycoprotein with a large extracellular domain (ECD) containing two CUB domains, and a smaller intracellular domain (ICD) containing five tyrosines. CDCP1 is widely expressed in human epithelial tissues, but its phosphorylation is only seen in mitotically detached or shedding cells, consistent with its role in the negative regulation of cell adhesion. The tyrosine phosphorylation of CDCP1 in cultured cells occurs when cells are induced to detach by trypsinor EDTA, or seen spontaneously during mitotic detachment. The overexpression of CDCP1 leads to the loss of cell adhesion and a detached phenotype.
CAS Number
9000-83-3
NCBI Gene ID
64866
Swiss Prot
Q9H5V8
Accession Number
Q9H5V8
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Signal Transduction, Stem Cell, Other
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
36.1 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
CUB domain containing protein 1
NCBI Organism
Homo sapiens
Other Product Names
CUB domain-containing protein 1, Membrane glycoprotein gp140, Subtractive immunization M plus HEp3-associated 135 kDa protein, SIMA135, Transmembrane and associated with src kinases, CD318, TRASK, C318
Species
Human
Protein ID
530379522
Physical Properties
Lyophilized

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