Cathepsin D Recombinant Protein

• Background:

  CTSD localizes to the lysosome and consists of a light chain and a heavy chain. CTSD is expressed in epithelial cells as well as in macrophages.CTSD is a lysosomal aspartyl protease that depends critically on protonation of its active site Asp residue and gets activated at pH 5 in endosome of hepatocytes. It has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix and xonnective tissue. In addition, CTSD has been used as a breast cancer tumor marker.

• NCBI Gene ID:

  13033

• Swiss Prot:

  P18242

• Accession Number:

  P18242

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM MES,150mM NaCl, pH5.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  43.9 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Cathepsin D

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Cathepsin D, CTSD, CPSD, CSTD

• Species:

  Mouse

• Protein ID:

  325652083

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3