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CLIC2 Recombinant Protein

CAT: 0223-91-246Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-91-246Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells; it regulatescellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions, channel activity depends on the pH. CLIC2 is involved in regulating membrane potential and organic solute transport. CLIC2 modulates the activity of RYR2 and inhibits Calcium influx. CLIC2 can be detected in the adult brain, liver, lung, heart, stomach, spleen and testis. It is expressed in fetal liver and adult skeletal muscle. CLIC2 is a potential candidate for one of many diseases linked to Xq28.
CAS Number
9000-83-3
NCBI Gene ID
1193
Swiss Prot
O15247
Accession Number
O15247
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 20% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
30.5 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Chloride intracellular channel 2
NCBI Organism
Homo sapiens
Other Product Names
Chloride Intracellular Channel Protein 2, XAP121, CLIC2
Species
Human
Physical Properties
Liquid

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