CLIC4 Recombinant Protein

• Background:

  Chloride Intracellular Channel Protein 4 (CLIC4) is a 253 amino acid single-pass membrane protein that localizes to both the nucleus and the cytoplasm and contains one GST C-terminal domain. CLIC4 is expressed in various tissues and exhibits an intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells) . CLIC4 acts as a monomer which is able to form selective ion channels in target proteins, thus facilitating the transport of chloride and other ions. CLIC4 is believed to have a role in apoptosis and is able to translocate to the nucleus under stress conditions. CLIC4 has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis.

• NCBI Gene ID:

  25932

• Swiss Prot:

  Q9Y696

• Accession Number:

  Q9Y696

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cell Cycle, Homeostasis, Obesity, Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  30.9 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Chloride intracellular channel 4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Chloride Intracellular Channel Protein 4, Intracellular Chloride Ion Channel Protein p64H1, CLIC4

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3