CD200 Recombinant Protein

• Background:

  CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.

• NCBI Gene ID:

  4345

• Swiss Prot:

  P41217

• Accession Number:

  AAH22522

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Immunology

• Purity:

  >98% as determined by SDS-PAGE.

• Buffer:

  PBS, pH7.4

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  23.4 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  CD200 molecule

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  McCaughan, G.W. et al., 1987, Immunogenetics 25:329-335.

• Background Reference 02:

  Chen, Z. et al., 2006, Mol Immunol. 43 (6) : 579-587.

• Background Reference 03:

  Wright GJ., et al., 2003, J. Immunol. 171 (6) : 3034–46.

• Other Product Names:

  CD200, MOX1, MOX2, MRC, OX-2, My033

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3