CD200 Antibody

• Background:

  The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.

• NCBI Gene ID:

  4345

• Swiss Prot:

  P41217

• Accession Number:

  P41217

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CD200 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-211 amino acids from the C-terminal region of human CD200.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  31 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CD200

• NCBI Official Name:

  OX-2 membrane glycoprotein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Dorfman, D.M., et al. Am. J. Clin. Pathol. 134 (5) :726-733 (2010)

• Background Reference 02:

  Wong, K.K., et al. J. Leukoc. Biol. 88 (2) :361-372 (2010)

• Background Reference 03:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 04:

  Koning, N., et al.Innate Immun 2 (2) :195-200 (2010)

• Other Product Names:

  OX-2 membrane glycoprotein, CD200, CD200, MOX1, MOX2

• Tested Applications:

  WB

• Protein ID:

  311033489

• Physical Properties:

  Liquid