CD155 Recombinant Protein

• Background:

  CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.

• NCBI Gene ID:

  5817

• Swiss Prot:

  P15151 (340I/M)

• Accession Number:

  NP_006496.2

• Tag:

  Mouse IgG2a Fc tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Immunology

• Buffer:

  Tris with Glycine, Arginine and NaCl, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  62.2 kDa

• Applications Notes:

  This recombinant protein can be used for E, WB. For research use only.

• NCBI Official Name:

  Poliovirus receptor isoform alpha precursor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zhang P., et al., 2008, Proc. Natl. Acad. Sci., 105 (47) : 18284-18289.

• Background Reference 02:

  Maier MK., et al., 2007, European Journal of Immunology, 37 (8) : 2214-2225.

• Background Reference 03:

  He Y., et al., 2000, Proc. Natl. Acad. Sci., 97 (1) : 79-84.

• Other Product Names:

  PVR, FLJ25946, PVS, CD155, TAGE4, HVED, NECL5

• Tested Applications:

  ELISA, WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3