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Recombinant human CD155/PVR protein

CAT: 0112-ATGP3644-050Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP3644-050Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PVR, also known as poliovirus receptor isoform alpha, is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. It catalyzes a large structural change in the virus that exposes membrane-binding protein chains. It plays an important regulatory role in helper T cell differentiation and allergic diseases. It is expressed in many types of human cells and has diverse functions. It may be potentially useful as a biomarker for cancer development and progression. It may play a critical role through both immunological and non-immuno logical mechanisms in pancreatic cancer. Recombinant human PVR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Name Alternative
Poliovirus receptor isoform alpha, PVR, CD155, HVED, Necl-5, NECL5, PVS, TAGE4, PVR cell adhesion molecule, Nectin-like protein 5
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
36.1 kDa (331aa)
Additionnal Information
PVR, Poliovirus receptor isoform alpha, PVR, CD155, HVED, Necl-5, NECL5, PVS, TAGE4, ATGP3644-10 µg, ATGP3644-20 µg, ATGP3644-50 µg, ATGP3644-100 µg, ATGP3644-250 µg, ATGP3644-500 µg, ATGP3644-1 mg, ATGP3644-10, ATGP3644-20, ATGP3644-50, ATGP3644-100, ATGP3644-250, ATGP3644-500, ATGP3644-1
References & Citations
Nishiwada S., et al. (2015) Anticancer Res. 35:2287-2297.; ; Strauss M., et al. (2015) J Virol. 89:4143-4157.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_006496
Uniprot Accession Number
P15151
Species
Human
N Terminal Sequence
Trp21
AA Sequence
WPPPGTGDVV VQAPTQVPGF LGDSVTLPCY LQVPNMEVTH VSQLTWARHG ESGSMAVFHQ TQGPSYSESK RLEFVAARLG AELRNASLRM FGLRVEDEGN YTCLFVTFPQ GSRSVDIWLR VLAKPQNTAE VQKVQLTGEP VPMARCVSTG GRPPAQITWH SDLGGMPNTS QVPGFLSGTV TVTSLWILVP SSQVDGKNVT CKVEHESFEK PQLLTVNLTV YYPPEVSISG YDNNWYLGQN EATLTCDARS NPEPTGYNWS TTMGPLPPFA VAQGAQLLIR PVDKPINTTL ICNVTNALGA RQAELTVQVK EGPPSEHSGM SRNLEHHHHH H

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