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Biglycan Recombinant Protein

CAT: 0223-91-353Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-353Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Biglycan is a 200-350 kD proteoglycan consisting of a 45 kD core protein and two chrondroitin/dermatan sulfate glycosaminoglycan chains. Biglycan binds to TGF-ß. It also binds to collagen type I in low ionic strength (less than 3 mM phosphate) buffer. At higher ionic strengths, Biglycan does not bind to collagen type I. It enhances the inhibition effect of TGF-ß on osteoclast proliferation at a concentration of 4-20 mg/ml. It also prevents the attachment of CHO cells to fibronectin, with a 50% inhibition at 17-21 mg/ml.
CAS Number
9000-83-3
NCBI Gene ID
633
Swiss Prot
P21810
Accession Number
P21810
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
40.47 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Biglycan
NCBI Organism
Homo sapiens
Other Product Names
Biglycan, Bone/Cartilage Proteoglycan I, PG-S1, BGN, SLRR1A
Species
Human
Protein ID
578877726
Physical Properties
Lyophilized

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