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Bc1-w Recombinant Protein

CAT: 0223-91-088Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-91-088Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
CAS Number
9000-83-3
NCBI Gene ID
599
Swiss Prot
Q92843
Accession Number
Q92843
Tag
C-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Cell Cycle
Buffer
Supplied as a 0.2 um filtered solution of 25mM HEPES, 100mM KCl, 20% Glycerol, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
19.87 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
BCL2 like 2
NCBI Organism
Homo sapiens
Other Product Names
Bcl-2-Like Protein 2, Bcl2-L-2, Apoptosis Regulator Bcl-W, BCL2L2, BCLW, KIAA0271, Bcl-2-Llike Protein 2
Species
Human
Physical Properties
Liquid

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