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Bcl-w Antibody

CAT: 0223-56-826Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-826Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Bcl-w is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.
NCBI Gene ID
599
Swiss Prot
Q92843
Accession Number
Q92843
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Bcl antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-59 amino acids from human Bcl.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Symbol
BCL2L2
NCBI Official Name
Bcl-2-like protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Denisov, A.Y., et al., J. Biol. Chem. 278 (23) :21124-21128 (2003) .
Background Reference 02
Hinds, M.G., et al., EMBO J. 22 (7) :1497-1507 (2003) .
Background Reference 03
Middleton, G., et al., Development 128 (3) :447-457 (2001) .
Background Reference 04
Ross, A.J., et al., Nat. Genet. 18 (3) :251-256 (1998) .
Other Product Names
Bcl-2-like protein 2, Bcl2-L-2, Apoptosis regulator Bcl-W, BCL2L2, BCLW, KIAA0271
Tested Applications
WB, IHC-P
Protein ID
296434404
Physical Properties
Liquid

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