BNIP3 Recombinant Protein

• Background:

  BCL2/Adenovirus E1B 19 kDa Protein-Iinteracting Protein 3 (BNIP3) is a single-pass membrane protein. BNIP3 is a member of the NIP3 family. BNIP3 contains a single Bcl-2 homology 3 domain and interacts with the E1B 19 kDa protein. BNIP3 have been associated with pro-apoptotic function. BNIP3 is an apoptosis-inducing protein that can overcome BCL2 suppression. It plays a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. BNIP3 involved in mitochondrial quality control via its interaction with SPATA18/MIEAP, response to mitochondrial damage, participates to mitochondrial protein catabolic process.

• NCBI Gene ID:

  664

• Swiss Prot:

  Q12983

• Accession Number:

  Q12983

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Autophagy, Cancer, Cell Cycle, Obesity

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  20.6 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  BCL2/adenovirus E1B 19kDa interacting protein 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3, BNIP3, NIP3

• Species:

  Human

• Protein ID:

  767904139

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3