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BNIP3 Antibody

CAT: 0223-56-927Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-927Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.
NCBI Gene ID
664
Swiss Prot
Q12983
Accession Number
Q12983
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This BNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-187 amino acids from human BNIP3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity, Autophagy
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Symbol
BNIP3
NCBI Official Name
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
NCBI Organism
Homo sapiens
Background Reference 01
References for protein:
Background Reference 02
Kothari, S., et al., Oncogene 22 (30) :4734-4744 (2003) .
Background Reference 03
Lee, S.M., et al., Life Sci. 71 (19) :2267-2277 (2002) .
Background Reference 04
Ray, R., et al., J. Biol. Chem. 275 (2) :1439-1448 (2000) .
Other Product Names
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BNIP3, NIP3
Tested Applications
WB, IHC-P, IF
Protein ID
20532402
Physical Properties
Liquid

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