Alpha-Taxilin Recombinant Protein

• Background:

  Alpha-Taxilin belongs to the taxilin family. alpha-Taxilin exists in almost all tissues, with higher expression levels observed in the heart, kidney, liver, and pancreas. alpha-Taxilin binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A, and STX4A, but not when these proteins are complexed with SNAP25, VAMP2 or STXBP1, suggesting that it interacts with syntaxins that do not form the SNARE complex. It is shown that alpha-Taxilin plays multiple roles in the generation and maintenance of neurons through modulation of the NAC-mediated translational machinary and/or the syntaxin-mediated vesicle traffic in the soma. In addition, alpha-Taxilin may be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.

• NCBI Gene ID:

  200081

• Swiss Prot:

  P40222

• Accession Number:

  P40222

• Tag:

  N, C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Neuroscience

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  20.4 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Taxilin alpha

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Alpha-Taxilin, TXLNA, TXLN, IL-14

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3