TGF-alpha Recombinant Protein

• Background:

  TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.

• NCBI Gene ID:

  7039

• Swiss Prot:

  P01135

• Accession Number:

  NP_001093161.1

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Growth Factors

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized TGF-alpha recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TGF-alpha is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TGF-alpha recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Transforming growth factor, alpha

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TFGA, Protransforming growth factor alpha, EGF-like TGF, TGF-alpha

• Species:

  Human

• Protein ID:

  153791414

• Physical Properties:

  Lyophilized