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Nilutamide (Standard)

CAT: 0804-HY-13702RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-13702RSize:1 Each
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Description
Nilutamide (Standard) is the analytical standard of Nilutamide. This product is intended for research and analytical applications. Nilutamide (Nilandron) is an orally active nonsteroidal androgen receptor antagonist with affinity for androgen receptors but not for progestogen, estrogen or glucocorticoid receptors. Nilutamide can be used to research prostate cancer. Nilutamide also has antischistosomal properties[1][4].
CAS Number
63612-50-0
Product Name Alternative
Nilandron (Standard) ; RU 23908 (Standard)
UNSPSC
12352005
Target
Androgen Receptor; Parasite; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Infection; Endocrinology
Assay Protocol
https://www.medchemexpress.com/nilutamide-standard.html
Smiles
O=C1N(C2=CC=C([N+]([O-])=O)C(C(F)(F)F)=C2)C(C(C)(C)N1)=O
Molecular Formula
C12H10F3N3O4
Molecular Weight
317.22
References & Citations
[1]Harris MG, et al. Nilutamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in prostate cancer. Drugs Aging. 1993 Jan-Feb;3 (1) :9-25.|[2]Babany G, et al. Inhibitory effects of nilutamide, a new androgen receptor antagonist, on mouse and human liver cytochrome P-450. Biochem Pharmacol. 1989 Mar 15;38 (6) :941-7.|[3]Simard J, et al. Comparison of in vitro effects of the pure antiandrogens OH-flutamide, Casodex, and nilutamide on androgen-sensitive parameters. Urology. 1997 Apr;49 (4) :580-6; discussion 586-9.|[4]Keiser J, Vargas M, Vennerstrom JL. Activity of antiandrogens against juvenile and adult Schistosoma mansoni in mice. J Antimicrob Chemother. 2010 Sep;65 (9) :1991-5.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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