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Nilutamide-d6

CAT: 0804-HY-13702S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13702S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nilutamide-d6 (Nilandron-d6) is the deuterium labeled Nilutamide. Nilutamide (Nilandron) is a non-steroidal anti-androgen agent proposed in the research of metastatic prostatic carcinoma[1][2].
CAS Number
1189477-66-4
UNSPSC
12352005
Hazard Statement
H302+H312+H332-H315-H319
Target
Androgen Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.77
Solubility
10 mM in DMSO|DMSO : ≥ 8.08mg/mL|Ethanol : ≥ 8.08mg/mL
Smiles
O=C1N(C2=CC(C(F)(F)F)=C(C=C2)[N+]([O-])=O)C(NC1(C([2H])([2H])[2H])C([2H])([2H])[2H])=O
Molecular Formula
C12H4D6F3N3O4
Molecular Weight
323.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Harris MG, et al. Nilutamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in prostate cancer. Drugs Aging. 1993 Jan-Feb;3 (1) :9-25.|[3]Ask K, et al. Metabolism of nilutamide in rat lung. Biochem Pharmacol. 2006 Jan 12;71 (3) :377-85.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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