p-MPPF (dihydrochloride)

• UNSPSC Description:

  p-MPPF dihydrochloride is a selective 5-HT antagonist that dose-dependently antagonizes the reduction of phosphorylated Erk1/2 levels in the hippocampus induced by 8-OH-DPAT (HY-112061) in rats. p-MPPF dihydrochloride can be used for neurological disease research[1].

• Target Antigen:

  5-HT Receptor; PERK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/p-mppf-dihydrochloride.html

• Smiles:

  O=C(N(CCN1CCN(C2=CC=CC=C2OC)CC1)C3=NC=CC=C3)C4=CC=C(F)C=C4.Cl.Cl

• Molecular Weight:

  507.43

• References & Citations:

  [1]Chen J, et al. 5-HT1A receptor-mediated regulation of mitogen-activated protein kinase phosphorylation in rat brain. Eur J Pharmacol. 2002 Oct 4;452(2):155-62.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  223699-41-0